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Index > Protein center > Mybpc3(Gene name) > Mouse
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  • Mybpc3 (Gene name),
  • Myosin-binding protein C, cardiac-type (Protein name ),  MYPC3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Mybpc3;
    Protein name:
    Myosin-binding protein C, cardiac-type(Cardiac MyBP-C);
    Alternative:
    C-protein, cardiac muscle isoform;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    1270
    Sequence:
    50:
    MPEPGKKPVS | AFNKKPRSAE | VTAGSAAVFE | AETERSGVMV | RWQRDGSDIT | 
    100:
    ANDKYGLAAE | GKRHTLTVRD | ASPDDQGSYA | VIAGSSKVKF | DLKVTEPAPP | 
    150:
    EKAESEVAPG | APEEVPAPAT | ELEESVSSPE | GSVSVTQDGS | AAEHQGAPDD | 
    200:
    PIGLFLMRPQ | DGEVTVGGSI | VFSARVAGAS | LLKPPVVKWF | KGKWVDLSSK | 
    250:
    VGQHLQLHDS | YDRASKVYLF | ELHITDAQTT | SAGGYRCEVS | TKDKFDSCNF | 
    300:
    NLTVHEAIGS | GDLDLRSAFR | RTSLAGAGRR | TSDSHEDAGT | PDFSSLLKKR | 
    350:
    DSFRRDSKLE | APAEEDVWEI | LRQAPPSEYE | RIAFQHGVEA | CHRPLKRLKG | 
    400:
    MKQDEKKSTA | FQKKLEPAYQ | VNKGHKIRLT | VELADPDAEV | KWLKNGQEIQ | 
    450:
    MSGSKYIFES | VGAKRTLTIS | QCSLADDAAY | QCVVGGEKCS | TELFVKEPPV | 
    500:
    LITRSLEDQL | VMVGQRVEFE | CEVSEEGAQV | KWLKDGVELT | REETFKYRFK | 
    550:
    KDGRKHHLII | NEATLEDAGH | YAVRTSGGQS | LAELIVQEKK | LEVYQSIADL | 
    600:
    AVGAKDQAVF | KCEVSDENVR | GVWLKNGKEL | VPDNRIKVSH | IGRVHKLTID | 
    650:
    DVTPADEADY | SFVPEGFACN | LSAKLHFMEV | KIDFVPRQEP | PKIHLDCPGS | 
    700:
    TPDTIVVVTG | NKLRLDVPIS | GDPAPTVVWQ | KTVTQGKKAS | AGPHPDAPED | 
    750:
    AGADEEWVFD | KKLLCETEGR | VRVETTKDRS | VFTVEGAEKE | DEGVYTVTVK | 
    800:
    NPVGEDQVNL | TVKVIDVPDA | PAAPKISNVG | EDSCTVQWEP | PAYDGGQPVL | 
    850:
    GYILERKKKK | SYRWMRLNFD | LLRELSHEAR | RMIEGVAYEM | RVYAVNAVGM | 
    900:
    SRPSPASQPF | MPIGPPGEPT | HLAVEDVSDT | TVSLKWRPPE | RVGAGGLDGY | 
    950:
    SVEYCQEGCS | EWTPALQGLT | ERRSMLVKDL | PTGARLLFRV | RAHNVAGPGG | 
    1000:
    PIVTKEPVTV | QEILQRPRLQ | LPRHLRQTIQ | KKVGEPVNLL | IPFQGKPRPQ | 
    1050:
    VTWTKEGQPL | AGEEVSIRNS | PTDTILFIRA | ARRTHSGTYQ | VTVRIENMED | 
    1100:
    KATLILQIVD | KPSPPQDIRI | VETWGFNVAL | EWKPPQDDGN | TEIWGYTVQK | 
    1150:
    ADKKTMEWFT | VLEHYRRTHC | VVSELIIGNG | YYFRVFSHNM | VGSSDKAAAT | 
    1200:
    KEPVFIPRPG | ITYEPPKYKA | LDFSEAPSFT | QPLANRSIIA | GYNAILCCAV | 
    1250:
    RGSPKPKISW | FKNGLDLGED | ARFRMFCKQG | VLTLEIRKPC | PYDGGVYVCR | 
    1270:
    ATNLQGEAQC | ECRLEVRVPQ | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Cardiac MyBP-C
    Cat.:
    E9964h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Cardiac MyBP-C
    MSDS:
    Please sign in first.
    ELISA Kit for Mouse Cardiac MyBP-C
    Cat.:
    E9964r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Cardiac MyBP-C
    Cat.:
    E9964m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Cardiac MyBP-C
    Cat.:
    U9964h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Cardiac MyBP-C
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Cardiac MyBP-C
    Cat.:
    U9964m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cardiac MyBP-C
    Cat.:
    U9964r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Cardiac MyBP-C
    Cat.:
    P9964Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cardiac MyBP-C
    Polyclonal Antibody for Mouse Cardiac MyBP-C
    Polyclonal Antibody for Mouse Cardiac MyBP-C
    Cat.:
    P9964Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Cardiac MyBP-C
    Monoclonal Antibody for Mouse Cardiac MyBP-C
    Monoclonal Antibody for Mouse Cardiac MyBP-C
    Monoclonal Antibody for Mouse Cardiac MyBP-C
    Protein for Mouse Cardiac MyBP-C
    Protein for Mouse Cardiac MyBP-C
    Protein for Mouse Cardiac MyBP-C
    Protein for Mouse Cardiac MyBP-C

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    References
    1. 1.
      "In vivo modeling of myosin binding protein C familial hypertrophic cardiomyopathy."
      Yang Q. , Sanbe A. , Osinska H. , Hewett T.E. , Klevitsky R. , Robbins J.
      Circ. Res.85:841-847(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: FVB.
      tissue: Heart muscle.
    2. 2.
      "Sequence of the cardiac isoform of murine myosin binding protein-C (MyBP-C) cDNA."
      McDonald K.S. , Hollander M.S. , Moss R.L.
      Submitted (1998-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Heart muscle.
    3. 3.
      "Top-down high-resolution mass spectrometry of cardiac myosin binding protein C revealed that truncation alters protein phosphorylation state."
      Ge Y. , Rybakova I.N. , Xu Q. , Moss R.L.
      Proc. Natl. Acad. Sci. U.S.A.106:12658-12663(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT MET-1;PHOSPHORYLATION AT SER-273; SER-282 AND SER-302
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